Retroviruses
 Overview about the retroviruses
 Retrovirus Structure (should be included diagram to show the structure clearly).
 Retrovirus classification (Should be included table).
 Retrovirus Mechanism and replications (also find the diagram or picture to explain the how to the virus can infect the host cell).
 ENVELOPE PROTEIN STRUCTURE (Diagram).

Human endogenous retroviruses
 Overview about the HERVS
• Definition
• Discovery of endogenous retroviruses.
• ORIGIN AND LOCALISATION (Including picture or Diagram showed the three main retro viral genes gag, pol and env, flanked by two long terminal repeats

(LTRs).
 Classification of HERVS (Including table to be clear).
 HERVS and cancers
 HERVS AND AUTOIMMUNITY
 BIOLOGICAL IMPORTANCE OF HERVS
 Cellular functions of HERVs
 HERVs as regulators of gene expression.
 THERAPEUTIC STRATEGIES

Then move to my gene interest:

 HERV-W (Syncytin 1).
• What is the syncytin1
• Function of the syncytin1
• Syncytin 1 and human disease (Including cancer and autoimmune disease).

I recommend the reference
 Retroviruses and insights into cancer (book): Jaquelin Dudley. (2011).
 There are many books talk about the basic, classification, replication and mechanism of retroviruses.
 I upload very interesting articles and review it will help you for write these introduction.

Note:
 Regarding to the diagram please can you draw the diagram by your own. Do not use any picture or diagram from books or articles.
 This introduction of my thesis, I would like to be organized and acceptable.
 Please could you avoid the plagiarism (it is very important).
 Use please the recently reference. Regarding to endogenous retroviruses I would like to use as much as you can from this articles

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1187282/ (Demystified . . . Human endogenous retroviruses, Review). I have uploaded you will find it.
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