Research Proposal on optimization the quality of anticoagulant in patient with Atrial fibrillation

    The research proposal should be: ABSTRACT – A brief summary ( around 50 words) of the research to be undertaken. It should preferably be written in non-technical language such that a non-specialist in the discipline will know what the proposal involves. SYNOPSIS OF LITERATURE – An introduction/synthesis of the key ideas & references that lead to the statement of the research question & objectives. (There is no specified maximum number of words, bear in mind this is not a literature review, and this section should be the minimum necessary to place the proposal in context) RESEARCH QUESTION/OBJECTIVES – State briefly & clearly the research question being asked & the objectives of the research. METHODOLOGY – A description of how the research will be undertaken. Sufficient detail of methods, and of sample size, source etc should be given so that it is clear how the methodology addresses the research aims.DATA COLLECTION AND ANALYSIS . The supervisor said about second( research proposal) uploaded form “I think that this has more potential but I’d be careful about limiting yourself to warfarin. The coming years, during which you’ll be completing your PhD, will see more use of the novel oral anticoagulants so I think that these need to be a focus to ‘future-proof’ your research. There will need to be education of patients about these new agents too, especially in relation to adherence as they typically have shorter half-lives than warfarin so missed doses will potentially have a much more significant impact on efficacy”. I’m also not sure about the truth of your statements “most pharmacists are not able to effectively advice their patients on issues associated with warfarin treatment”, and “Improved pharmacist education on warfarin management is the only effective way to optimize the use of it to improve patients’ adherence to their treatment regimen”. Is the problem that pharmacists don’t know enough about warfarin, or is it that they simply don’t have adequate opportunities to educate patients on warfarin? We’ve already done some work in the area of pharmacist home visits incorporating warfarin education in any case – please see attached. What I’d suggested, as mentioned below, is initially the development of a prospective database to evaluate patients’ diet, antithrombotic knowledge, anticoagulation satisfaction and adherence. This database can then be used to identify patient outcomes and subsequently what the actual nature of any problems are – is it a lack of information provided by healthcare professionals, or is it that healthcare professionals don’t have sufficient opportunities to follow patients up to repeat the important messages, or is it other factors interfering with adherence? You can then plan lack an intervention to address these actual real world problems.
    -Use about 5 -10 references ( articles) and do not focus only on warfarin.

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