Evolution of vaccine development against pneumococcal pneumonia.


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    Evolution of vaccine development against pneumococcal pneumonia.

    Topic: Evolution of vaccine development against pneumococcal pneumonia.
    -The word limit is 4000-6000 words.
    -Provide me or send to me all references that you will use in my paper because I need the abstract for each reference you will use.
    -Table of content is needed.
    These are the organization and outlines for the assignment:
    – Abstract.
    • Introduction to the topic:
    • Background information about pneumococcal pneumonia infection:
    • The causative agent
    • Disease syndromes caused by it.
    • Characteristics of the diseases.
    • Manifestations of the disease.
    • Diagnosis and the current therapeutic strategies of the disease.
    • Epidemiology including the spread, worldwide incidence, prevalence, pandemic, significance to the public health and the economic cost.
    • Source and reservoir+ incubation period.
    • Modes of the transmission of the pathogen.
    • Mechanisms of pathogenesis:
    • Virulence factors and those that need attention in vaccine development.
    • Risk factors.
    • People at risk.
    • Evolution of vaccine development against pneumococcal infection:
    • Immunization and prophylaxis against pneumonia.
    • Serotype diversity.
    • The specificity of immune response against serotypes.
    • Types of vaccines undergoing trials.
    • Immunization schedule.
    • Current vaccines undergoing trials.
    • Their benefits and limitations.
    • The novel alternatives for third generation pneumococcal vaccines.
    • Burden and cost effectiveness of vaccination.
    • Current status of the development of improved vaccines and the ways by which the improved vaccines will be better than the currently used vaccines.
    • Discussion:- Indicate all of previous different evolutions.
    • Conclusion + future directions for vaccine development.

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