“Optogenetics”

    “Optogenetics”
    specifically.
    which is ( Zemelman, B. V., Lee, G. A., Ng, M., & Miesenböck, G. (2002). Selective photostimulation of genetically charged neurons. Neuron. 33(1):15-22.)
    Gene Therapy He, C., Tan, C., Wang, F., Wang, Y., Zhou, R., Cui, D., You, W., Zhao, H., Ren,
    J., & Feng B. (2016). Knock-in of large reporter genes in human cells via
    CRISPR/Cas9-induced homology-dependent and independent DNA repair.
    Nucleic Acids Res.
    Simonelli, F., Maguire A. M., Testa, F., Pierce, E. A., Mingozzi, F., Bennicelli, J.
    L., Rossi, S., Marshall, K., Banfi, S., Surace, E. M., Sun, J., Redmond, M.
    T., Zhu, X., Shindler, K. S., Ying, G., Ziviello, C., Ace2rra, C., Wright, J.
    F., McDonnell, J. W., High, K. A., Bennett, J., & Auricchio, A. (2010).
    Gene Therapy for Leber’s Congenital Amaurosis is Safe and Effective
    Through 1.5 Years After Vector Administration. Mol Ther. 18(3): 643-650
    Buchanan, A., & Powell, R. (2011). Breaking evolution’s chains: the prospect of
    deliberate genetic modification in humans. J Med Philos. 2011
    February; 36(1): 6–27.
    De Melo, S. M., Bittencourt, S., Ferrazoli, E. G., da Silva, C. S., da Cunha, F. F.,
    da Silva, F. H., … Han, S. W. (2015). The Anti-Tumor Effects of Adipose
    Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-
    Driven Brain Tumor. PLoS ONE, 10(6)
    (G)FP
    Transgenics
    Phillios, J. G. (2001). Green fluorescent protein–a bright idea for the study of
    bacterial protein localization. FEMS Microbiol Lett. 204(1): 9–18.
    Fourrage, C., Swann, K., Gonzalez Garcia, J. R., Campbell, A. K., & Houliston,
    E. (2014). An endogenous green fluorescent protein–photoprotein pair
    in Clytia hemisphaerica eggs shows co-targeting to mitochondria and
    efficient bioluminescence energy transfer. Open Biology, 4(4), 130206.
    http://doi.org.proxy1.lib.uwo.ca/10.1098/rsob.130206
    Hoffman, R. M. (2015). Application of GFP imaging in cancer. Laboratory
    Investigation; a Journal of Technical Methods and Pathology, 95(4), 432–
    452. http://doi.org.proxy1.lib.uwo.ca/10.1038/labinvest.2014.154
    Shaner NC, Steinbach PA, Tsien RY (Dec 2005). “A guide to choosing
    fluorescent proteins” (PDF). Nature Methods 2 (12): 905–9.
    Synthetic
    Biology
    Gibson, D. G., Benders, G. A., Andrews-Pfannkoch, C., Denisova, E. A., BadenTillson,
    H., Zaveri, J., Smith, H. O.(2008). Complete Chemical Synthesis,
    Assembly, and Cloning of a Mycoplasma genitalium
    Genome. Science,319(5867), 1215–1220
    Church, G. M., Gao, Y., & Kosuri, S. (2012). Next-generation digital information
    storage in DNA. Science. 337(6102):1628
    University of Western Ontario Bio1202B Literacy
    Koder, R. L., Ross Anderson, J. L., Solomon, L. A., Reddy, K. S., Moser, C. C.,
    & Dutton, P. L. (2009). Design and engineering of an O(2) transport
    protein.Nature, 458(7236), 305–309
    Nguyen, P. Q., Botyanszki, Z., Tay, P. R., Joshi, N. S. (2014). Programmable
    biofilm-based materials from engineered curli nanofibres. Nat Commun. 5:
    4945
    Forensics Hara, M., Nakanishi, H., Yoneyma, K., Saito, K., & Takada, A. (2016). Effects of
    storage conditions on forensic examinations of blood samples and
    bloodstains stored for 20 years. Leg Med (Tokyo). 18:81-4
    Miller, K. W., Dawson, J. L., & Hagelberg, E. (1996). A concordance of
    nucleotide substitutions in the first and second hypervariable segments of
    the human mtDNA control region. Int J Legal Med. 109(3): 107–113.
    Pontes, M. L., Fondevila, M., Laréu, M. V., & Medeiros, R. (2015). SNP Markers
    as Additional Information to Resolve Complex Kinship Cases.Transfusion
    Medicine and Hemotherapy, 42(6), 385–388.
    Wang, Z., Zhou, D., Zhang, S., Bian, Y., Gu, Z., Zhu, R., Lu, D., & Li, C. (2015).
    Logical Framework of Forensic Identification: Ability to Resist
    Fabricated DNA. Mol Biotechnol. 57, 11-12
    Genetically
    Modified
    Animals
    Lazaris, A., Arcidiacono, Yue Huang, Y,. Zhou, J., Duguay, F., Chretien, N.,
    Welsh, E. A., Soares, J. W., & Karatzas, C. N. (2002). Spider silk
    fibers spun from soluble recombinant silk produced in mammalian
    cells. Science. 295(5554): 472–476
    S. P. Golovan, R. G. Meidinger, A. Ajakaiye, M. Cottrill, M. Z. Wiederkehr, D. J.
    Barney, C. Plante, J. W. Pollard, M. Z. Fan, M. A. Hayes, et al.
    (2001). Pigs expressing salivary phytase produce low-phosphorus
    manure. Nat Biotechnol. 8: 741–745
    Tong, C., Li, P., Wu, N. L., Yan, Y., & Ying, Q. L. (2010). Production
    of p53gene knockout rats by homologous recombination in embryonic
    stem cells. Nature, 467(7312), 211–213
    Irving, A. A., Yoshimi, K., Hart, M. L., Parker, T., Clipson, L., Ford, M. R., &
    Amos-Landgraf, J. M. (2014). The utility of Apc-mutant rats in
    modeling human colon cancer. Disease Models & Mechanisms, 7(11),
    1215–1225.
    Genetically
    Modified
    Plants
    Subramoni, S., Nathoo, N., Klimov, E., & Yuan, Z.-C. (2014). Agrobacterium
    tumefaciens responses to plant-derived signaling molecules. Frontiers in
    Plant Science, 5, 322.
    Wang, C., Zeng, J., Li, Y., Hu, W., Chen, L., Miao, Y., … He, G. (2014).
    Enrichment of provitamin A content in wheat (Triticum aestivum L.) by
    introduction of the bacterial carotenoid biosynthetic
    University of Western Ontario Bio1202B Literacy
    genes CrtB and CrtI .Journal of Experimental Botany, 65(9), 2545–2556.
    Zou. S., Huang. K., Xu, W., Luo, Y., & He, X. (2015). Safety assessment of
    lepidopteran insect-protected transgenic rice with cry2A*gene. Transgenic
    Res.
    Römer, S., Fraser, P. D., Kiano, J. W., Shipton, C. A., Misawa, N., Schuck, W.,
    Bramley, P. M. (2000). Elevation of the provitamin A content of transgenic
    tomato plants. Nat Biochmol. 18(6): 666-669
    Genetically
    Modified
    Microbes
    Walsh, G. (2005). Therapeutic insulins and their large-scale manufacture. Appl
    Microbiol Biotechnol. 67(2): 151–159
    Hillman, J. D. (2002). Genetically modified Streptococcus mutans for the
    prevention of dental caries. Antonie Van Leeuwenhoek. 82(1-4): 361–366
    Ruiz, O. N., Alvarez, D., Gonzalez-Ruiz, G., & Torres, C. (2011).
    Characterization of mercury bioremediation by transgenic bacteria
    expressing metallothionein and polyphosphate kinase. BMC
    Biotechnology, 11, 82
    Fears, R., & Ter Meulen, V. (2015). European academies advise
    on Gain of Function studies in influenza virus research. J. Virol.
    Pharming Büttner-Maninik, A., Parsons, J., Jérôme, H., Hartmann, A., Lamer, S., Schaaf,
    A., Schlosser, A., Zipfel, P. F., Reski, R., & Decker, E. L. (2001).
    Production of Biologically active recombinant human factors H in
    Physomitrella. Plant Biotechnol J. 9(3): 373-383.
    Cox, K. M., Sterling, J. D., Regan, J. T., Gasdaska, J. R., Frantz, K. K., Peele, C.
    G., Black, A., Passmore, D., Moldovan-Loomis, C., Srinivasan, M.,
    Cuison, S., Cardarlli, P. M., & Dickey, L. F. (2006). Glycan optimization
    of a human monoclonal antibody in the aquatic plant Lemna minor. Nat
    Biotechnol. 24(12): 1591–1597
    Gregory, J. A., Li, F., Tomosada, L. M., Cox, C. J., Topol, AB, et
    al. (2012) Algae-Produced Pfs25 Elicits Antibodies That Inhibit Malaria
    Transmission. PLoS ONE 7(5)
    Sung, Y.Y., & Lee, C. S. (2013). Mammary Gland-Specific Expression of
    Biologically Active Human Osteoprotegerin in Transgenic
    Mice. Development & Reproduction, 17(1), 1–8.
    Personal
    Genomics
    Mantere, T., Winqvist, R., Kauppila, S., Grip, M., Jukkola-Vuorinen, A.,
    Tervasmäki, A., & Pylkäs, K. (2016). Targeted Next-Generation
    Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with
    Hereditary Breast Cancer Susceptibility. PLoS Genetics, 12(1)
    Baptista, N. M., Christensen, K. D., Carere, D. A., Broadley, S. A., Roberts, J.
    S., & Green R. C. (2016). Adopting genetics: motivations and outcomes of

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